Ketamine works fast, and fades fast
In an early randomized trial, a single ketamine infusion improved symptoms of treatment-resistant depression within about two hours, and about a third of participants were still responding a week later [1]. That pattern is why ketamine care is usually delivered as a series of sessions rather than a single one.
Animal research points the same way. In mice, the window of heightened learning that psychedelics reopen lasted about 48 hours after ketamine, shorter than after psilocybin, LSD, or MDMA [2]. If the window is short, the days right after each session matter even more.
Why the days between sessions matter
Between sessions, clients go back to the same stress, routines, and habits that brought them in. Integration conversations help, but they are often spread out. A short daily practice in those days gives clients something concrete to do with the openness a session brings, and gives their care team a way to see how they are doing.
How Psio supports ketamine care
- Measure. A comfortable EEG headband records brain activity before, during, and after the session, giving each person a personal starting point.
- Personalize. Psio turns those recordings into a training program built for that person and that session.
- Train at home. About twelve minutes a day of guided neurofeedback with the headband and the Psio app, during the weeks when change is easiest to keep.
- Track change. The client and their care team see progress over time and use it to guide what comes next.
For ketamine clinics
- Recurring touchpoints between sessions, without adding appointments to your calendar.
- Before-and-after brain measurements across the whole series, so progress is visible to your team and your client.
- No qEEG lab to build and no technician to hire. Psio provides the headband pathway, software, protocols, and Psio Academy training.
- Hardware-agnostic and substance-agnostic, so it fits the care you already deliver.
